In this study, we introduce novel method of flow cytometry for cell detection based on\nimpedance measurements. The state of the art method for impedance flow cytometry detection\nutilizes an embedded electrode in the microfluidic to perform measurement of electrical impedance\nof the presence of cells at the sensing area. Nonetheless, this method requires an expensive and\ncomplicated electrode fabrication process. Furthermore, reuse of the fabricated electrode also requires\nan intensive and tedious cleaning process. Due to that, we present a microfluidic device with\nintegrated microneedles. The two microneedles are placed at the half height of the microchannel\nfor cell detection and electrical measurement. A commercially-available Tungsten needle was\nutilized for the microneedles. The microneedles are easily removed from the disposable PDMS\n(Polydimethylsiloxane) microchannel and can be reused with a simple cleaning process, such as\nwashing by ultrasonic cleaning. Although this device was low cost, it preserves the core functionality\nof the sensor, which is capable of detecting passing cells at the sensing area. Therefore, this device is\nsuitable for low-cost medical and food safety screening and testing process in developing countries.
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